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oryz-aspergillus enzyme + pancreatin + ursodeoxycholic acid
- Development stage
- Unknown
- Lead developer
- Edward Keller
- Modality
- Replacement Enzymes → Therapeutic Enzymes → Recombinant Proteins and Enzymes, Small Molecules
- Administration
- Oral
01
Overview
This is a combination drug containing oryz-aspergillus enzyme (a fungal-derived digestive enzyme blend), pancreatin (a mixture of pancreatic enzymes including amylase, lipase, and protease), and ursodeoxycholic acid (a bile acid). The combination is designed to aid digestion in patients with reduced digestive capacity due to conditions such as dyspepsia, malnutrition associated with cirrhosis, or other gastrointestinal disorders. Oryz-aspergillus enzymes help break down carbohydrates and proteins; pancreatin supplements endogenous pancreatic enzymes for fat, protein, and carbohydrate digestion; ursodeoxycholic acid improves bile flow and reduces cholesterol absorption by modifying the composition of bile acids. This combination has been studied for improving symptoms in functional dyspepsia and malnutrition related to liver disease[1][3][4][8].
- Brand names
- CombizymFESTAL PLUS
- Other names
- oryz-aspergillus enzyme and pancreatin tabletoryz-aspergillus enzyme + pancreatin + ursodeoxycholic acid
02
Targets
FXR (Farnesoid x-activated receptor)GPBAR1
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