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oxomemazine + guaifenesin + potassium iodate
- Development stage
- Unknown
- Lead developer
- EMS
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Oxomemazine + guaifenesin + potassium iodate is an oral fixed-dose cough syrup evaluated for **acute cough**. Oxomemazine is a first-generation phenothiazine antihistamine with sedating and antimuscarinic activity, principally antagonizing histamine H1 receptors; guaifenesin is an expectorant intended to facilitate clearance of respiratory secretions; and potassium iodate was described in the registered study as an expectorant component. The combination was investigated by EMS in the completed randomized, open-label phase 3 study NCT01257243, which compared the combination with guaifenesin monotherapy over seven days in adults with acute cough.
- Other names
- guaifenesin + oxomemazine + potassium iodateoxomemazine + guaifenesin + potassium iodate syrupoxomemazine + potassium iodate + guaifenesinoxomemazina + guaifenesina + iodato de potássio
02
Targets
HRH1 (Histamine H1 Receptor)
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