oxycodone + ciprofol

The combination of oxycodone and ciprofol is an anesthetic regimen primarily investigated for use in painless artificial abortion procedures. Ciprofol (HSK3486) is a novel intravenous anesthetic agent and a GABAA receptor agonist, developed as an alternative to propofol with a higher potency and potentially improved safety profile, including reduced injection pain and respiratory depression. Oxycodone is a semi-synthetic opioid agonist that acts primarily on mu-opioid receptors to provide potent analgesia. When used together, oxycodone provides preemptive analgesia, which allows for a reduction in the required dose of ciprofol, thereby enhancing the quality of anesthesia and reducing the incidence of adverse events such as respiratory depression and hemodynamic instability during short surgical procedures like artificial abortion.

Other names

oxycodone hydrochloride + ciprofol