oxycodone + hydromorphone

oxycodone + hydromorphone refers to the narcotic-based pain management protocol utilized by the University of Arizona in clinical research (notably NCT04843306) for the treatment of postoperative pain in patients undergoing robotic bariatric surgery. This multimodal regimen involves the administration of oral oxycodone for moderate to severe pain and intravenous hydromorphone (Dilaudid) for breakthrough pain. Both agents are opioid analgesics that primarily function as agonists at the mu-type opioid receptor, inhibiting ascending pain pathways and altering the perception of and response to pain. The protocol is studied as a standard-of-care comparator against non-narcotic alternatives to evaluate its impact on recovery, nausea, and 30-day surgical outcomes in patients undergoing elective sleeve gastrectomy.

Brand names

Dilaudid

Other names

narcotic-University of Arizona-postoperative painnarcotic regimennarcotic pain management protocol