oxycodone + parecoxib sodium

This is a combination therapy consisting of oxycodone (an opioid analgesic) and parecoxib sodium (a selective COX-2 inhibitor). The combination represents a multimodal analgesic approach for managing postoperative pain. Parecoxib sodium is a water-soluble injectable prodrug of valdecoxib that provides anti-inflammatory, analgesic, and antipyretic effects through selective inhibition of COX-2[2][4]. Oxycodone acts on the central nervous system to relieve pain[3]. When used together, this combination can provide effective pain relief while potentially reducing opioid consumption and opioid-related adverse effects[6][7].