oxytocin + tranexamic acid

This is not a standard combination drug product but rather two separate medications (oxytocin and tranexamic acid) that are sometimes considered for co-administration in the treatment of postpartum hemorrhage (PPH). Research has shown significant interaction between certain oxytocin and tranexamic acid products when mixed, leading to reduction in oxytocin concentration (14.8%-29.0%) immediately upon mixing. This interaction could result in underdosing of oxytocin in emergency situations. Until the exact nature of this interaction is understood, mixing these medications for co-administration with intravenous infusion fluids should be avoided.

Brand names

Hexakapron

Other names

Hexakapron + oxytocinTXA + oxytocin