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ozone (Premier Research Laboratories)
- Development stage
- Unknown
- Lead developer
- Yunus Burak Bayır
- Modality
- Small Molecules
- Administration
- Perineural Injection
01
Overview
Ozone (O3) is a triatomic form of oxygen used in medical therapy for its potent anti-inflammatory, analgesic, and immunomodulatory properties. In the context of carpal tunnel syndrome (CTS), medical ozone is typically administered via ultrasound-guided perineural injection into the space surrounding the median nerve. The mechanism of action involves the modulation of oxidative stress, inhibition of pro-inflammatory cytokines (such as TNF-alpha and IL-1beta), and enhancement of local microcirculation. This specific application is being investigated by Yunus Burak Bayır in a randomized, triple-blind clinical trial comparing the effectiveness of ozone injections against corticosteroids and 5% dextrose for the management of moderate CTS symptoms.
- Brand names
- Ozene
- Other names
- O3O-3O 3medical ozonetriatomic oxygen
02
Targets
KEAP1 (Kelch-like ECH-associated protein 1)NFE2L2 (Nuclear factor (erythroid-derived 2)-like 2)
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