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P1-(5'-Adenosyl)P5-(5'-(3'azido-3'-Deoxythymidyl))Pentaphosphate

Development stage: Unknown
Modality: Small Molecules

Overview

P1-(5'-Adenosyl)P5-(5'-(3'azido– -deoxythymidylpentaphosphate is a synthetic dinucleotide analog in which adenosine and a modified thymidine (bearing an azido group at the 3’ position and lacking the normal hydroxyl group there) are linked via a pentaphosphate bridge. It is classified as an experimental small molecule and has not been approved for clinical use. The compound has been used primarily as a biochemical tool to study nucleotide interactions with enzymes such as thymidylate kinase but does not have any known therapeutic indications or established mechanism of action in humans[2][4].

Other names: P1-(5'-ADENOSYL)P5-(5'-(3'AZIDO-3'-DEOXYTHYMIDYL))PENTAPHOSPHATE(((2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl)methoxy-oxidophosphoryl)(((((2S,3S,5R)-3-azido– -deoxythymidylpentaphosphate[1][2][4]

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