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palmitoylethanolamide + resveratrol

Development stage: Unknown
Lead developer: Gencor
Modality: Small Molecules
Administration: Oral

Overview

Levagen + resveratrol is an oral nutraceutical combination developed by RDC Global Pty Ltd, specifically designed to address pain and inflammation associated with menstrual disorders. The product combines Levagen+, a highly bioavailable formulation of palmitoylethanolamide (PEA) utilizing LipiSperse® dispersion technology, with the polyphenolic antioxidant resveratrol. PEA is an endogenous fatty acid amide that exerts analgesic and anti-inflammatory effects by modulating endocannabinoid-like receptors and prostaglandin-mediated pathways. The LipiSperse® technology enhances the bioavailability of PEA by approximately 1.75 times compared to standard formulations. This combination is currently being evaluated in a Phase 3/4 clinical trial for the treatment of primary dysmenorrhea in adult women.

Brand names: Levagen + resveratrol
Other names: PEA + resveratrol

Targets

GPR55 (G protein-coupled receptor 55)PPARA (Peroxisome proliferator-activated receptor alpha)

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