Drug intelligence / Profile preview

pancrelipase (Impax Laboratories)

Development stage
Unknown
Lead developer
Amneal Pharmaceuticals
Modality
Replacement Enzymes → Therapeutic Enzymes → Recombinant Proteins and Enzymes
Administration
Oral
01

Overview

Lipram is a brand name for pancrelipase, a porcine-derived pancreatic enzyme replacement therapy (PERT). It consists of a mixture of digestive enzymes, including lipase, amylase, and protease, which are essential for the digestion of fats, carbohydrates, and proteins. Lipram is specifically indicated for the treatment of exocrine pancreatic insufficiency (EPI), a condition where the pancreas does not produce enough enzymes to properly digest food. This condition is frequently associated with cystic fibrosis, chronic pancreatitis, pancreatectomy, or other gastrointestinal surgeries. The medication is typically formulated as enteric-coated capsules to prevent the enzymes from being inactivated by gastric acid, allowing them to be released in the duodenum where they facilitate nutrient absorption.

Brand names
LipramLipram-CR5Lipram-CR-5Lipram-CR 5Lipram-CR10Lipram-CR-10Lipram-CR 10Lipram-CR20Lipram-CR-20Lipram-CR 20Lipram-PN10Lipram-PN-10Lipram-PN 10Lipram-UL18Lipram-UL-18Lipram-UL 18Lipram 4500Lipram4500Lipram-4500
Other names
pancreatinpancreatic enzymes
02

Targets

Dietary starch and related linear alpha-1,4-linked polysaccharides

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