paracetamol + caffeine

Paracetamol + caffeine is a fixed-dose combination of two active ingredients: paracetamol (also known as acetaminophen), an analgesic and antipyretic, and caffeine, a central nervous system stimulant. This combination is primarily used for the short-term relief of moderate pain such as headaches, migraines, muscle aches, menstrual pain, toothaches, backaches, colds and sore throats. Paracetamol works by inhibiting prostaglandin synthesis in the central nervous system or by activating descending serotonergic pathways to reduce pain perception. Caffeine acts as a vasoconstrictor in the brain to reduce headache and also enhances the analgesic effect of paracetamol[1][2][5]. The combination provides more effective symptom management than either agent alone.

Brand names

DoloDoloparStopacheNovalgin NUCafiparCipmolZimalginTrimol SBinilonParatuf Active

Other names

acetaminophen + caffeine