paracetamol + metamizole + ketorolac

This entry refers to the specific analgesic regimen used as the control arm in a clinical trial (NCT02684305) conducted by the Hospital General Naval de Alta Especialidad - Escuela Medico Naval. The regimen consists of a combination of three non-opioid analgesics: paracetamol (acetaminophen), metamizole (dipyrone), and ketorolac. Paracetamol and metamizole are primarily used for their analgesic and antipyretic properties, while ketorolac is a potent non-steroidal anti-inflammatory drug (NSAID) that provides significant postoperative pain relief. The combination works by inhibiting cyclooxygenase (COX) enzymes, thereby reducing the synthesis of pro-inflammatory prostaglandins. This specific protocol was evaluated in pediatric patients aged 6 to 14 years undergoing surgery to compare its efficacy against laughter therapy in reducing postoperative pain, anxiety, and hospital stay duration.

Other names

Conventional treatment-Hospital General Naval de Alta Especialidad - Escuela Medico NavalConventional treatment