Paracetamol + phenylephrine

Paracetamol + phenylephrine is a fixed-dose combination of two small molecule drugs commonly used for the symptomatic relief of colds and influenza. Paracetamol (also known as acetaminophen) acts as an analgesic and antipyretic, reducing pain (such as headache, sore throat, muscle aches) and fever. Phenylephrine is a sympathomimetic amine that acts as a nasal decongestant by constricting blood vessels in the nasal passages, thereby reducing swelling and congestion. This combination does not treat the underlying cause of infection but provides temporary relief from symptoms such as headache, body aches, feverishness, sore throat pain, sinus congestion, and blocked nose[1][2][5][8].

Brand names

Alka-Seltzer Plus Cold and SinusExcedrin Sinus HeadacheSudafed PE Pressure Plus PainAcetaminophen Congestion and PainMygrex

Other names

acetaminophen + phenylephrineparacetamol/phenylephrine hydrochloride