Drug intelligence / Profile preview

paradichlorobenzene + benzocaine + chlorobutanol + turpentine oil

Development stage
Unknown
Lead developer
Ordain Health Care Global
Modality
Small Molecules
Administration
Otic
01

Overview

Ceruklin is a combination otic solution developed and marketed by Ordain Health Care (a division of Exeltis) for the treatment of impacted earwax (cerumen). The formulation contains four active components: paradichlorobenzene, which acts as a cerumenolytic to soften and disintegrate hardened wax; benzocaine, a local anesthetic that alleviates ear pain and discomfort; chlorobutanol, which provides preservative and mild local anesthetic effects; and turpentine oil, which serves as a solvent and lubricant to facilitate wax removal. It is primarily indicated for patients experiencing hearing loss, ear fullness, or pain due to excessive cerumen accumulation.

Brand names
Ceruklin
Other names
Ceruklin Ear Drops
02

Targets

NaV (Voltage-gated sodium channels)Cerumen lipid matrix

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