Drug intelligence / Profile preview

particulate xenograft + erythropoietin

Development stage
Preclinical
Lead developer
Amgen
Modality
Recombinant Proteins and Enzymes
Administration
Intravenous, Subcutaneous, Surgical Implantation
01

Overview

This appears to be a combination therapy involving particulate xenograft material and erythropoietin. Erythropoietin is a recombinant form of human erythropoietin used to increase differentiation of progenitor cells to red blood cells in the treatment of anemia. Studies have investigated the effect of erythropoietin on tumor growth in xenograft models, with findings suggesting that epoetin β (a form of recombinant human erythropoietin) does not enhance tumor growth in xenograft models using EPO-receptor positive human cancer cell lines. The combination therapy may be investigated for potential applications in cancer treatment or other medical conditions.

02

Targets

Erythropoietin Receptor

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