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Patent Blue V + Sienna

Development stage: Unknown
Lead developer: Guerbet
Modality: Inorganic Nanoparticles → Nanoparticles → Drug Delivery Systems, Small Molecules
Administration: Peritumoral, Subareolar, Intradermal, Subcutaneous

Overview

Patent Blue V + Sienna is a combination used for sentinel lymph node identification before biopsy in patients with operable breast cancer. Patent Blue V is a blue dye that is selectively absorbed into the lymphatics, bound to albumin, and excreted into the urine and bile. It helps visualize lymphatic vessels and sentinel nodes. Sienna (also known as Sienna+) is a magnetic tracer used with the Sentimag device for sentinel lymph node detection. The combination technique improves detection rates compared to using either agent alone.

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