Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
Patient-Controlled IV Analgesia-Children's Mercy Hospital Kansas City-postoperative pain refers to a specific multi-modal analgesic protocol developed and evaluated at Children's Mercy Hospital Kansas City for managing postoperative pain, particularly in pediatric patients undergoing minimally invasive pectus excavatum repair (the Nuss procedure). This strategy was designed as an alternative to thoracic epidural analgesia. The protocol involves the intraoperative administration of fentanyl for anesthesia induction, followed by postoperative hydromorphone delivered via a patient-controlled analgesia (PCA) pump. The PCA system allows for both a continuous background infusion and patient-triggered demand doses. Additionally, for patients weighing more than 35 kg, the protocol incorporates a transdermal clonidine patch to provide non-opioid synergistic analgesia. Clinical trials conducted at the hospital have shown that this PCA-based approach provides comparable pain relief to epidural analgesia with potential advantages in terms of reduced hospital stay and cost-effectiveness.
Beyond the preview
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Follow clinical development from study design and recruitment through results.
Explore development by indication, patient population, and geography.
Trace asset ownership, licensing agreements, and commercial partnerships.
Explore the patent landscape and regulatory exclusivity around an asset.
Compare development programs by target, modality, and indication.
Connect source evidence and development news to your research questions.
See how Gosset can support your research on Patient-Controlled IV Analgesia-Children's Mercy Hospital Kansas City-postoperative pain.