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PCV 3p+0 refers to a specific dosing regimen for the pneumococcal conjugate vaccine (PCV) evaluated in clinical research led by Nagasaki University. This schedule involves the administration of three primary doses of the vaccine during infancy without a subsequent booster dose. In the context of the Evaluation of PCV Schedules in a Naive Population in Vietnam study, this regimen serves as a comparator to evaluate the effectiveness of reduced-dose schedules (such as 1p+1 or 0p+1) in maintaining herd immunity and preventing the reintroduction of vaccine-type Streptococcus pneumoniae following a catch-up campaign. The vaccine utilized in these studies is generally the 10-valent pneumococcal conjugate vaccine (PCV10), which provides protection against invasive pneumococcal disease and pneumonia caused by ten specific serotypes of the bacteria.
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