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PCV-LITE + LVA

Development stage: Unknown
Lead developer: LiteVax
Modality: Recombinant Proteins and Enzymes, Vaccines & Immunotherapeutics
Administration: Intramuscular

Overview

**PCV-LITE + LVA** is a novel, low-dose pneumococcal conjugate vaccine formulation composed of one-fifth the standard dose of the 20-valent pneumococcal conjugate vaccine (PCV20) combined with 1 mg of LiteVax Adjuvant (LVA). It is designed to enhance the immunogenicity of low-dose PCV20 using the LVA immunoadjuvant. The vaccine is delivered as a single intramuscular injection, and its primary objective is to elicit a strong immune response against *Streptococcus pneumoniae* using less antigen through adjuvantation. The product is in Phase 1 clinical development to assess its safety, tolerability, and immunogenicity as compared to full-dose and non-adjuvanted controls. PCV-LITE + LVA is being developed by LiteVax, as indicated by ongoing clinical trials in healthy adults[1][8].

Brand names: PCV-LITE + LVA
Other names: PCV-LITE + LVA

Targets

TCR (T cell antigen receptor complex)TLR2 (Toll-like Receptor 2)

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