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pegylated liposomal doxorubicin + adebrelimab
- Development stage
- Preclinical
- Lead developer
- Johnson & Johnson
- Modality
- Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
- Administration
- Intravenous
01
Overview
A combination therapy consisting of pegylated liposomal doxorubicin and adebrelimab. Pegylated liposomal doxorubicin is a formulation of doxorubicin encapsulated in pegylated liposomes, which increases circulation time and alters the toxicity profile compared to conventional doxorubicin. Adebrelimab is likely a monoclonal antibody immunotherapy agent.
02
Targets
TOP2A (DNA topoisomerase II)CD274 (Programmed cell death protein 1 ligand 1)
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