Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
pegylated zinc(ii) phthalocyanine 1b
- Development stage
- Unknown
- Modality
- Small Molecules
- Administration
- Intravenous, Subcutaneous, Intratumoral
01
Overview
Pegylated zinc(II) phthalocyanine 1b (ZnPc 1b) is a research-stage small molecule photosensitizer designed for use in photodynamic therapy (PDT). It consists of a zinc(II) phthalocyanine core substituted with polyethylene glycol (PEG) chains to improve water solubility and biocompatibility. Upon irradiation with specific wavelengths of light, the molecule generates reactive oxygen species (ROS), primarily singlet oxygen, which induces cytotoxicity in targeted cancer cells. In vitro studies have demonstrated its phototoxic effects against various cancer cell lines, including colorectal adenocarcinoma (HT29), hepatocarcinoma (HepG2), and head and neck cancer (A253, FaDu). It is currently utilized as a laboratory tool in academic research and as a precursor for more complex functionalized derivatives.
- Other names
- ZnPc 1bZnPc1bZnPc-1bdi-beta-substituted zinc(II) phthalocyanine bearing polyethylene glycol chains
02
Targets
^1O2 (Singlet oxygen)
Beyond the preview
Go deeper on pegylated zinc(ii) phthalocyanine 1b.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on pegylated zinc(ii) phthalocyanine 1b.