Drug intelligence / Profile preview

pepsin + thiamine

Development stage
Unknown
Lead developer
Chengdu Tongde Pharmaceutical
Modality
Small Molecules, Recombinant Proteins and Enzymes
Administration
Oral
01

Overview

Compound Pepsin (marketed as Tongde Wei by Chengdu Tongde Pharmaceutical) is an oral combination formulation consisting of pepsin and thiamine (Vitamin B1). It is primarily used as a digestive aid to treat indigestion, loss of appetite, and dyspepsia, particularly in pediatric populations. Pepsin is a proteolytic enzyme that functions in the acidic environment of the stomach to catalyze the hydrolysis of dietary proteins into smaller peptides. Thiamine serves as an essential coenzyme (thiamine pyrophosphate) in carbohydrate metabolism and is vital for maintaining normal gastrointestinal motility and digestive function. The product is approved and widely used in China for symptomatic relief of digestive disorders.

Brand names
Tongde Wei通德为
Other names
Compound Pepsin Granules复方胃蛋白酶颗粒
02

Targets

α-KGDH (Alpha-ketoglutarate dehydrogenase complex)PEP (Pepsin)PDH (Pyruvate dehydrogenase complex)TKT (Transketolase)OGDH (Dihydrolipoamide S-succinyltransferase)

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