Drug intelligence / Profile preview

perflutren (ImaRx Therapeutics, Inc.)

Development stage
Unknown
Lead developer
ImaRx Therapeutics
Modality
Small Molecules
Administration
Intravenous
01

Overview

Definity (perflutren lipid microsphere) is an ultrasound contrast agent (microbubble agent) developed by ImaRx and marketed by Lantheus. It consists of lipid microspheres encapsulating perflutren, a perfluorocarbon gas. When administered intravenously, these microbubbles enhance the echogenicity of blood, improving the visualization of vascular structures and tissue perfusion during ultrasound imaging. Definity is FDA-approved as an echocardiographic contrast agent for cardiac imaging (left ventricular opacification and endocardial border delineation) in both adult and pediatric patients. It has also been investigated for other diagnostic applications, including the characterization of thyroid nodules using contrast-enhanced ultrasound (CEUS).

Brand names
DefinityDefinity RTLuminity
Other names
octafluoropropaneoctafluoropropane-lipid microsphereperflutren lipid microsphereperflutren lipid microspheres

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