Drug intelligence / Profile preview

PerioPatch (Izun Pharmaceuticals)

Development stage
Unknown
Lead developer
Izun Pharma
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Topical
01

Overview

PerioPatch is a topically applied, mucoadhesive herbal patch designed to treat localized oral inflammatory conditions such as gingivitis and periodontitis. Developed by Izun Pharma, the patch contains a proprietary blend of herbal extracts—including *Centella asiatica*, *Echinacea purpurea*, and *Sambucus nigra*—that act to reduce inflammation and promote tissue healing. It works by forming a physical barrier over the affected area while releasing active ingredients that inhibit inflammatory enzymes like beta-glucuronidase and matrix metalloproteinases (MMPs). The patch is designed to adhere to the oral mucosa, providing sustained delivery of its botanical components directly to the site of inflammation to reduce symptoms such as bleeding and swelling.

Brand names
PerioPatch
Other names
PerioPatch
02

Targets

GUSB (Beta-glucuronidase)MMP12 (Macrophage Metalloelastase)

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