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personalized parenteral nutrition (Ospedali Riuniti Ancona)
- Development stage
- Unknown
- Lead developer
- Azienda Ospedaliero-Universitaria delle Marche
- Modality
- Small Molecules
- Administration
- Intravenous
01
Overview
Personalized parenteral nutrition (P-PN) is a tailored intravenous nutritional therapy used in the management of preterm infants. In the context of the Phase IV clinical trial conducted by Ospedali Riuniti Ancona (NCT03693287), P-PN involves the individual prescription and pharmacy-compounding of essential nutrients to meet the specific metabolic and growth requirements of infants with a birth weight greater than 1250 grams. The formulation typically includes dextrose 50% as a glucose source, Primene as an amino acid source, and Clinoleic as a lipid emulsion. This personalized approach is compared against standardized, ready-to-use multi-chamber bag formulations (such as Numeta G13%E) to evaluate its impact on neonatal growth and nutritional outcomes. The therapy provides essential macronutrients and micronutrients directly into the bloodstream when enteral feeding is insufficient or contraindicated.
- Other names
- personalized-parenteral nutrition-Ospedali Riuniti Ancona-prematurityPersonalized-parenteral nutrition
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