Drug intelligence / Profile preview

Pfizer Research & Development MET compound 13

Development stage
Preclinical
Lead developer
Pfizer
01

Overview

Pfizer Research & Development MET compound 13: sourced facts only. name: "Compound 13 with a MET D1228N cell line IC50 value of 23 nM showed good efficacy in an intracranial tumor model and increased the median overall survival of the animals to 100% when dosed orally at 100 mg/kg daily for 21 days." [PMID:39088797]; target: "Compound 13 with a MET D1228N cell line IC50 value of 23 nM showed good efficacy in an intracranial tumor model and increased the median overall survival of the animals to 100% when dosed orally at 100 mg/kg daily for 21 days." [PMID:39088797]; developer: "Pfizer Research & Development 3200 Walnut Street, Boulder, Colorado 80301, United States." [PMID:39088797]; stage: "Compound 13 with a MET D1228N cell line IC50 value of 23 nM showed good efficacy in an intracranial tumor model and increased the median overall survival of the animals to 100% when dosed orally at 100 mg/kg daily for 21 days." [PMID:39088797]

02

Targets

MET (Mesenchymal-epithelial transition factor receptor)

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