Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
phenylephrine + apocynin
- Development stage
- Unknown
- Lead developer
- The University of Texas at Arlington
- Modality
- Small Molecules
- Administration
- Local
01
Overview
Phenylephrine + apocynin is an experimental drug combination used in clinical research to investigate the role of oxidative stress in vascular function. Phenylephrine acts as a selective alpha-1 adrenergic receptor agonist, inducing vasoconstriction. Apocynin is a phytochemical that functions as an inhibitor of NADPH oxidase (NOX), an enzyme responsible for the production of superoxide radicals. By co-administering these agents, researchers at The University of Texas at Arlington aim to determine if NADPH oxidase-derived oxidative stress contributes to the heightened vasoconstrictor responses observed in certain populations, such as Black/African American individuals, which may be linked to increased cardiovascular disease risk.
- Other names
- Phenylephrine and Apocynin
02
Targets
NOX4 (NADPH oxidase 4)ADRA1A (α1A)
Beyond the preview
Go deeper on phenylephrine + apocynin.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on phenylephrine + apocynin.