Drug intelligence / Profile preview

phenylephrine + Ringer-Acetate

Development stage
Unknown
Modality
Small Molecules
Administration
Intravenous
01

Overview

Phenylephrine + Ringer-Acetate is a combination of the vasopressor and decongestant phenylephrine with the balanced electrolyte solution Ringer-Acetate. Phenylephrine is an alpha-1 adrenergic receptor agonist that induces vasoconstriction, raising blood pressure and reducing nasal congestion by narrowing blood vessels[1][3]. It is used intravenously to treat hypotension, especially in surgical or critical care settings. Ringer-Acetate is an isotonic crystalloid solution containing sodium chloride, potassium chloride, calcium chloride dihydrate, magnesium chloride, and sodium acetate in water; it serves as a plasma volume expander to replace fluids and electrolytes lost due to illness or injury[5]. The combination may be used in intensive care for hemodynamic support where both fluid resuscitation and vasopressor therapy are required.

02

Targets

ADRA1A (α1A)

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