phenylephrine + tropicamide

Phenylephrine + tropicamide is a fixed-dose ophthalmic mydriatic combination. Tropicamide is a muscarinic anticholinergic that inhibits cholinergic constriction of the iris sphincter and ciliary muscle, while phenylephrine hydrochloride is an alpha-1 adrenergic agonist that contracts the iris dilator muscle. Together, they produce short-term pupillary dilation for diagnostic ophthalmic procedures and other settings requiring mydriasis. The FDA-approved microdose ophthalmic-spray presentation is marketed in the United States as MydCombi, containing tropicamide 1% and phenylephrine hydrochloride 2.5% and delivered using Eyenovia's Optejet dispenser. ([accessdata.fda.gov](https://www.accessdata.fda.gov/drugsatfda_docs/label/2023/215352s000lbl.pdf))

Brand names

MydCombi

Other names

MicroStatphenylephrine hydrochloride + tropicamidephenylephrine/tropicamidetropicamide + phenylephrinetropicamide + phenylephrine hydrochloridetropicamide/phenylephrine盐酸苯肾上腺素 + 托吡卡胺