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**Phytopica** is an oral veterinary botanical product originally developed by Phytopharm for canine skin health and atopic dermatitis. It is a proprietary, chemically heterogeneous blend of standardized plant extracts rather than a single defined molecular entity. In a randomized, double-blind, placebo-controlled 12-week study in 120 dogs with perennial canine atopic dermatitis, the product code **PYM00217** produced a statistically significant reduction in CADESI disease-severity scores at 200 mg/kg/day; no serious adverse effects were reported, although mild gastrointestinal events occurred more frequently at higher doses. ([pubmed.ncbi.nlm.nih.gov](https://pubmed.ncbi.nlm.nih.gov/16827666/))
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