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This refers to the combination of citalopram, a selective serotonin reuptake inhibitor (SSRI) antidepressant, administered together with a placebo. In clinical trials, this typically means patients receive active citalopram alongside an inert substance (placebo) for comparison or blinding purposes. Citalopram acts by inhibiting the reuptake of serotonin in the brain, thereby increasing its availability and improving mood symptoms in conditions such as major depressive disorder. The combination is not a marketed pharmaceutical product but rather a research protocol used to assess efficacy and safety of citalopram versus other treatments or combinations[4][5].
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