placebo + risperidone

This is a combination of placebo and risperidone. Risperidone is an atypical (second-generation) antipsychotic medication used primarily to treat schizophrenia, bipolar disorder, and irritability associated with autism spectrum disorder. It works mainly by antagonizing dopamine D2 receptors and serotonin 5-HT2A receptors in the brain, leading to changes in neurotransmitter activity that help regulate mood, behavior, and thought processes. Placebo is an inert substance with no active pharmacological effect; it is commonly used as a control in clinical trials to assess the efficacy of active medications like risperidone[1][2][3][6][7].