placebo + topical corticosteroids

placebo + TCS refers to a control treatment regimen used in clinical trials, particularly for atopic dermatitis. It consists of an inactive placebo (often administered via subcutaneous injection to match the investigational biologic) and the background use of topical corticosteroids (TCS). TCS are a standard-of-care class of anti-inflammatory medications that bind to glucocorticoid receptors to reduce skin inflammation, pruritus, and redness. In the context of LEO Pharma's Phase 3 trials for tralokinumab, this combination serves as the comparator arm to evaluate the efficacy and safety of adding a specific IL-13 inhibitor to standard topical therapy in pediatric and infant populations.

Other names

placebo + TCS