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placenta-derived mesenchymal stem cells (Institute of Cell Therapy)
- Development stage
- Unknown
- Lead developer
- Institute of Cell Therapy
- Modality
- Stem Cell Therapies → Cell Therapies
- Administration
- Intraarticular
01
Overview
This investigational cell therapy consists of cryopreserved human placenta-derived mesenchymal stem cells (hP-MSCs) developed by the Institute of Cell Therapy in Kyiv, Ukraine. It is specifically being evaluated for the treatment of stage II-III knee osteoarthritis. The therapy involves the intra-articular injection of allogeneic cells that possess multipotent properties, allowing them to differentiate into chondrocytes, osteoblasts, and adipocytes. These cells are intended to promote cartilage regeneration and provide immune-suppressive and anti-inflammatory effects within the joint. In clinical trials (NCT04453111), the product is administered in a series of three injections at four-week intervals, often in conjunction with hyaluronic acid to enhance therapeutic outcomes.
- Other names
- hP-MSCsplacenta-derived multipotent mesenchymal stem / stromal cellsP-MMSCs
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