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platelet-rich plasma (Buddhist Tzu Chi General Hospital)

Development stage
Unknown
Lead developer
Buddhist Tzu Chi General Hospital
Modality
Cell Therapies
Administration
Intravesical
01

Overview

This is an investigational autologous platelet-rich plasma (PRP) therapy developed by **Buddhist Tzu Chi General Hospital** (Hualien Tzu Chi Hospital) for the treatment of refractory **interstitial cystitis/bladder pain syndrome (IC/BPS)**. The therapy involves extracting PRP from the patient's own whole blood and administering it via intravesical injections directly into the bladder wall. PRP is a concentrated source of autologous growth factors—including PDGF, VEGF, and TGF-beta—and cytokines that are believed to facilitate tissue reconstruction and regeneration of the damaged bladder urothelium. Clinical studies led by Dr. Hann-Chorng Kuo have evaluated its safety and efficacy in patients who have failed conventional treatments, showing improvements in pain scores and bladder capacity.

Other names
PRPautologous platelet-rich plasmaintravesical platelet-rich plasma
02

Targets

FGFR (FGFR family)TGFBR (TGF-beta receptor)VEGFR (VEGFR family)ERBB2 (Erb-b2 receptor tyrosine kinase 2)PDGFRA (Platelet-derived growth factor receptor alpha)

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