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Platelet-rich plasma (PRP) is an autologous biologic therapy derived from a patient's own blood, processed to achieve a high concentration of platelets. These platelets serve as a reservoir for numerous growth factors, including platelet-derived growth factor (PDGF), transforming growth factor-beta (TGF-β), and vascular endothelial growth factor (VEGF), which are released upon activation to stimulate tissue repair, modulate inflammation, and promote nerve regeneration. In the clinical trial context led by Sheikh Zayed Medical College, PRP is utilized as an injectable treatment for carpal tunnel syndrome. It is typically administered via ultrasound-guided hydrodissection around the median nerve, aiming to provide long-term symptomatic relief by facilitating the recovery of the nerve and reducing perineural fibrosis.
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