polyethylene glycol + elobixibat

Polyethylene glycol + elobixibat is a combination therapy used primarily as a bowel preparation regimen for colonoscopy. Polyethylene glycol (PEG) is an osmotic laxative that retains water in the stool, resulting in softer stools and increased bowel movements. Elobixibat is an ileal bile acid transporter inhibitor that increases the amount of bile acids entering the colon, stimulating colonic secretion and motility. The combination has been shown to provide effective bowel cleansing with good tolerability and less frequent sleep disturbance compared to other regimens such as sodium picosulfate plus PEG[1][2][3]. This regimen is considered an alternative option for patients requiring colonoscopy preparation.

Other names

polyethylene glycol plus elobixibatPEG + elobixibatPEG-Asc + elobixibat