Drug intelligence / Profile preview

polyethylene glycol 400 (Johnson & Johnson)

Development stage
Phase 4
Lead developer
Alcon
Modality
Implantable Hydrogels → Hydrogel Systems → Drug Delivery Systems, Small Molecules, Non-biodegradable Polymers → Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems, Biodegradable Polymers → Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems, Injectable Hydrogels → Hydrogel Systems → Drug Delivery Systems
Administration
Ophthalmic
01

Overview

Blink Gel Tears is an over-the-counter lubricating eye drop formulation designed to provide relief for moderate to severe dry eye symptoms. The primary active ingredient is polyethylene glycol 400 (0.25%), which acts as a lubricant and humectant to supplement the natural tear film and reduce ocular surface desiccation. A distinguishing feature of the Blink Gel Tears formulation is the inclusion of sodium hyaluronate (hyaluronic acid), which enhances the viscosity and mucoadhesive properties of the drop, allowing it to stay on the ocular surface longer than standard artificial tears. It also utilizes the OcuPure preservative system, which dissipates upon contact with light, making it gentler on the eyes than traditional preservatives like benzalkonium chloride. It is indicated for the temporary relief of burning, irritation, and discomfort due to dryness of the eye or exposure to wind or sun.

Brand names
Blink Gel Tears
Other names
PEG 400PEG400PEG-400

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