Drug intelligence / Profile preview

potassium chloride + sodium acetate + sodium chloride + magnesium chloride + sodium gluconate

Development stage
Unknown
Lead developer
Takeda
Modality
Small Molecules
Administration
Intravenous, Topical
01

Overview

Potassium chloride + sodium acetate + sodium chloride + magnesium chloride + sodium gluconate is a **sterile, isotonic balanced crystalloid electrolyte solution** marketed primarily as **Plasma-Lyte A** for intravenous administration and as **Physiolyte** for irrigating use. It is a **small-molecule mineral salt combination product** developed and marketed by Baxter and also marketed in irrigant form by B. Braun. The formulation supplies sodium, potassium, magnesium, chloride, acetate, and gluconate to expand and maintain extracellular fluid volume, correct or prevent electrolyte depletion, and provide an alkalinizing effect because acetate and gluconate are metabolized to bicarbonate precursors. Clinically it is used in adults and pediatric patients as a source of water and electrolytes for hydration and correction of dehydration or electrolyte imbalance, and in irrigant presentations for general irrigation, rinsing, and washing.

Brand names
Plasma-Lyte APhysiolyte
Other names
multiple electrolytes injection type 1multiple electrolytes injection type 1 pH 7.4plasmalyte abalanced multi-electrolyte solutionphysiological irrigating solution

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