Drug intelligence / Profile preview

potassium chloride + sodium lactate + sodium chloride + calcium chloride + dextrose

Development stage
Approved
Lead developer
Pfizer
Modality
Small Molecules
Administration
Intravenous, Parenteral
01

Overview

**Potassium chloride + sodium lactate + sodium chloride + calcium chloride + dextrose** is a fixed-combination intravenous crystalloid solution marketed as **Lactated Ringers and Dextrose** and **Potassium Chloride in Lactated Ringers and Dextrose**. It is a pharmaceutical multi-electrolyte and carbohydrate parenteral fluid composed of inorganic salts plus dextrose, developed and marketed by Hospira. The product is used as a source of water, electrolytes, and calories, for parenteral replacement of extracellular fluid and electrolyte losses, and as an alkalinizing agent. Its pharmacologic effect is supportive rather than receptor-targeted: sodium, potassium, calcium, chloride, and lactate help restore fluid and electrolyte balance, while dextrose provides carbohydrate calories; lactate is metabolized to bicarbonate precursors and contributes an alkalinizing effect. It is supplied as a single-dose intravenous injection or infusion solution for adult and pediatric use.

Brand names
Lactated Ringers and DextrosePotassium Chloride in Lactated Ringers and Dextrose
Other names
potassium chloride + sodium lactate + sodium chloride + calcium chloride + dextrosePotassium Chloride in Lactated Ringer's and Dextrose InjectionPotassium Chloride in Lactated Ringer's and Dextrose 5% InjectionPotassium Chloride in Lactated Ringer's and DextroseLactated Ringer's and Dextrose 5% InjectionLactated Ringers and Dextrose 5% Injection
02

Targets

SLC16A1 (Mitochondrial Pyruvate Carrier)

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