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potassium citrate + sodium citrate hydrate
- Development stage
- Phase 4
- Lead developer
- MADAUS
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Potassium citrate + sodium citrate hydrate is an oral fixed-dose alkalinizing medicine containing two citrate salts. Citrate is metabolized to bicarbonate, increasing systemic and urinary alkalinity and urinary citrate availability. It is marketed in Japan as Uralyt-U and Uralyt for improvement of acidic urine associated with gout or hyperuricemia and for improvement of metabolic acidosis. It has also been clinically studied for prevention of calcium stone recurrence and contrast-induced nephropathy, while preclinical studies have examined tumor-microenvironment alkalinization and chemotherapy-induced peripheral neuropathy.
- Brand names
- QuenmetUralytUralyt-U
- Other names
- K/Na citrateNa/K citratePCSCpotassium citrate/sodium citratepotassium citrate/sodium citrate hydratepotassium sodium citratesodium potassium citrate
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