Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
This is a combination product containing three active ingredients: - **Potassium nitrate** is an inorganic salt that serves as a source of nitrate, which can be converted in the body to nitric oxide, leading to vasodilation and improved blood flow. - **Propionyl-L-carnitine** is an acylated form of L-carnitine involved in mitochondrial fatty acid transport and energy production. It has been studied for its effects on peripheral vascular disease, heart failure, angina, and exercise performance by improving mitochondrial function and muscle energy metabolism[6][9][10]. - **Nicotinamide riboside** is a precursor to nicotinamide adenine dinucleotide (NAD+), essential for cellular metabolism and mitochondrial function. Supplementation increases NAD+ levels, supporting metabolic health. The combination aims to synergistically enhance vascular perfusion (via nitric oxide from nitrates), improve mitochondrial fatty acid oxidation (via propionyl-L-carnitine), and boost cellular energy metabolism (via increased NAD+ from nicotinamide riboside). This approach targets conditions characterized by impaired perfusion or metabolic dysfunction such as heart failure with preserved ejection fraction (HFpEF)[1], obesity-related liver disease[2][3], or possibly other cardiovascular/metabolic disorders.
Beyond the preview
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Follow clinical development from study design and recruitment through results.
Explore development by indication, patient population, and geography.
Trace asset ownership, licensing agreements, and commercial partnerships.
Explore the patent landscape and regulatory exclusivity around an asset.
Compare development programs by target, modality, and indication.
Connect source evidence and development news to your research questions.
See how Gosset can support your research on potassium nitrate + propionyl-L-carnitine + nicotinamide riboside.