Drug intelligence / Profile preview

povidone-iodine + isopropyl alcohol + lidocaine hydrochloride + bupivacaine hydrochloride

Development stage
Unknown
Lead developer
Asclemed USA
Modality
Small Molecules
Administration
Topical, Percutaneous
01

Overview

povidone-iodine + isopropyl alcohol + lidocaine hydrochloride + bupivacaine hydrochloride is a multi-component anesthetic and antiseptic kit formulation, exemplified by products like the **DYURAL 40 KIT**. This combination product is designed for the production of local or regional anesthesia while providing broad-spectrum skin antisepsis. The anesthetic components, **lidocaine hydrochloride** and **bupivacaine hydrochloride**, are amide-type local anesthetics that work by blocking voltage-gated sodium channels, thereby inhibiting nerve impulse initiation and conduction. The antiseptic components, **povidone-iodine** and **isopropyl alcohol**, are used for pre-operative skin preparation to reduce the risk of procedural site infection. These kits are typically marketed by companies such as **Asclemed USA** (Enovachem) and are often categorized as unapproved drugs by the FDA, meaning their specific combination labeling has not undergone formal FDA approval for safety and efficacy.

Brand names
DYURAL 40 KITDYURAL40 KITDYURAL-40 KITDYURAL 80 KITDYURAL80 KITDYURAL-80 KIT
02

Targets

Kir (Inward-rectifier potassium channels)NaV (Voltage-gated sodium channels)

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