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povidone-iodine + isopropyl alcohol + lidocaine hydrochloride + dexamethasone sodium phosphate
- Development stage
- Unknown
- Modality
- Small Molecules
- Administration
- Topical
01
Overview
**Povidone-iodine + isopropyl alcohol + lidocaine hydrochloride + dexamethasone sodium phosphate** is a multi-ingredient pharmaceutical combination marketed as **Dexlido**, combining two topical antiseptics or disinfectants, a local anesthetic, and a corticosteroid. Based on the provided context, the therapeutically consequential component is dexamethasone sodium phosphate, a water-soluble synthetic glucocorticoid that activates the glucocorticoid receptor to produce anti-inflammatory and immunosuppressive effects, while lidocaine hydrochloride provides local sodium-channel blockade and povidone-iodine plus isopropyl alcohol provide local antimicrobial skin preparation activity. The product appears to be an unapproved drug product for which FDA has not found safety and effectiveness and has not approved labeling. The supplied disease context largely reflects systemic dexamethasone injection labeling rather than a clearly validated development program specific to this exact four-ingredient combination product.
- Brand names
- Dexlido
- Other names
- povidone-iodine + isopropyl alcohol + lidocaine hydrochloride + dexamethasone sodium phosphate
02
Targets
GR (Glucocorticoid receptor)NaV alpha (Voltage-gated sodium channel alpha subunit family)MR (Mineralocorticoid receptor)
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