Drug intelligence / Profile preview

povidone-iodine + isopropyl alcohol + lidocaine hydrochloride + methylprednisolone

Development stage
Unknown
Lead developer
Asclemed USA
Modality
Small Molecules
Administration
Intramuscular, Intraarticular, Intralesional, Parenteral, Topical
01

Overview

This product is a **combination injectable kit** built around **methylprednisolone acetate injectable suspension** together with **lidocaine hydrochloride** for local anesthetic effect and **povidone-iodine** plus **isopropyl alcohol** as antiseptic skin-preparation components. The pharmacologically dominant therapeutic ingredient is methylprednisolone, a synthetic glucocorticoid corticosteroid that exerts anti-inflammatory and immunosuppressive effects primarily through activation of the glucocorticoid receptor and downstream transcriptional regulation. Based on the provided context, this combination appears to correspond to kit-based products such as **DYURAL 40 KIT** associated with **Asclemed USA**, intended for office-based injection procedures including intramuscular, intra-articular, soft tissue, or intralesional administration. The kit context is tied to the established labeled uses of methylprednisolone acetate across a broad range of inflammatory, allergic, rheumatologic, dermatologic, hematologic, renal, respiratory, ophthalmic, and neoplastic conditions, but the specific four-component kit formulation itself was described as **not approved by the FDA as safe and effective**.

Other names
povidone-iodine + isopropyl alcohol + lidocaine hydrochloride + methylprednisolone
02

Targets

MR (Mineralocorticoid receptor)NaV (Voltage-gated sodium channels)GR (Glucocorticoid receptor)

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