Drug intelligence / Profile preview

prednisolone + methylprednisolone + deflazacort

Development stage
Unknown
Lead developer
Marathon Pharmaceuticals
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
Administration
Oral, Intravenous, Intramuscular
01

Overview

This is a combination of three synthetic glucocorticoids (prednisolone, methylprednisolone, and deflazacort) that have anti-inflammatory and immunosuppressive properties. Each drug works by decreasing inflammation and modifying the body's immune response. Methylprednisolone is a derivative of prednisolone, while deflazacort is an oxazoline derivative of prednisolone. These corticosteroids have different potencies and conversion ratios between them.

02

Targets

GR (Glucocorticoid receptor)

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