Drug intelligence / Profile preview

prednisolone + prednisone + methylprednisolone

Development stage
Unknown
Lead developer
Bayer HealthCare Pharmaceuticals
Modality
Small Molecules
Administration
Oral, Intravenous, Intramuscular, Intraarticular, Soft Tissue Injection
01

Overview

This is a combination of three corticosteroid medications (prednisolone, prednisone, and methylprednisolone) that reduce inflammation and suppress the immune system. They work by modifying glucocorticoid receptors and suppressing mediators of inflammation. Methylprednisolone is slightly more potent than prednisone, with methylprednisolone being five times as potent as cortisol, while prednisone is four times as potent. These medications are used to treat various inflammatory and autoimmune conditions including rheumatoid arthritis, lupus, allergic reactions, asthma, and other disorders.

Brand names
Depo-MedrolPrelone
02

Targets

GR (Glucocorticoid receptor)

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