Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
pregabalin + vitamin b
- Development stage
- Unknown
- Lead developer
- Pfizer
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
A combination of the alpha-2-delta ligand pregabalin and vitamin B complex (comprising thiamine, pyridoxine, and cyanocobalamin) utilized by Laboratorios Silanes. Pregabalin acts by binding to the alpha-2-delta subunit of voltage-gated calcium channels in the central nervous system, which reduces the influx of calcium into nerve terminals and subsequently inhibits the release of excitatory neurotransmitters involved in pain signaling. The vitamin B complex components are included for their neurotropic properties, which support nerve regeneration and provide additional analgesic benefits in neuropathic conditions. This specific combination is currently being evaluated in a Phase III clinical trial (NCT06516094) as a comparator arm to a triple fixed-dose combination (celecoxib/pregabalin/vitamin B) for the management of chronic low back pain with a mixed neuropathic and nociceptive component.
- Other names
- pregabalin + vitamin b complexpregabalin + thiamine + pyridoxine + cyanocobalamin
02
Targets
CACNA2D1 (Voltage-gated calcium channel subunit alpha2/delta-1)CACNA2D2 (α2δ-2)
Beyond the preview
Go deeper on pregabalin + vitamin b.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on pregabalin + vitamin b.