Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
PRF + polyhexanide + macrogol
- Development stage
- Unknown
- Lead developer
- Medical University of Vienna
- Modality
- Injectable Hydrogels → Hydrogel Systems → Drug Delivery Systems, Implantable Hydrogels → Hydrogel Systems → Drug Delivery Systems, Non-biodegradable Polymers → Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems, Small Molecules, Biodegradable Polymers → Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems
- Administration
- Topical
01
Overview
PRF + polyhexanide + macrogol is an investigational combination therapy developed by the Medical University of Vienna for the treatment of infected chronic venous ulcers. The treatment utilizes autologous Platelet Rich Fibrin (PRF) as a biologic scaffold and delivery vehicle. PRF is derived from the patient's own blood via centrifugation and contains a concentrated matrix of fibrin, platelets, leukocytes, and various growth factors (such as PDGF, TGF-β, and VEGF) that promote tissue regeneration and wound healing. In this specific formulation, the PRF matrix is impregnated with Lavasorb®, a topical antiseptic solution containing polyhexanide (PHMB) and macrogol. Polyhexanide serves as a broad-spectrum antimicrobial agent that disrupts bacterial cell membranes, while macrogol acts as a surfactant to facilitate wound cleansing and enhance the distribution of the antiseptic within the wound bed.
- Brand names
- Lavasorb
- Other names
- PRF mixed with PHMB plus MacrogololPRF + LavasorbPlatelet Rich Fibrin + polyhexanide + macrogol
02
Targets
PDGFR (PDGFR family)TGFBR (TGF-beta receptor)VEGFR (VEGFR family)
Beyond the preview
Go deeper on PRF + polyhexanide + macrogol.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on PRF + polyhexanide + macrogol.