progesterone + drospirenone

Progesterone + drospirenone refers to a combination of the natural steroid hormone progesterone and the synthetic progestin drospirenone. While not a standard fixed-dose combination in clinical practice, this terminology appears in clinical literature (e.g., case reports) to describe progestogen-based hormonal therapy, particularly in the context of oral contraceptives used for conditions like thoracic endometriosis syndrome (TES). Drospirenone is a spironolactone analogue with antimineralocorticoid and antiandrogenic activity, while progesterone is the endogenous agonist of the progesterone receptor. In the management of endometriosis, these agents work by suppressing the growth of endometrial tissue and inhibiting ovulation. The use of the term "progesterone" in this context often serves as a broad descriptor for progestogens rather than specifically referring to the endogenous hormone molecule.

Other names

progesterone-drospirenone